Membrane Chaperoning by Members of the PspA/IM30 Protein Family

verfasst von
Adrien Thurotte, Thomas Brüser, Thorsten Mascher, Dirk Schneider
Abstract

PspA, IM30 (Vipp1) and LiaH, which all belong to the PspA/IM30 protein family, form high molecular weight oligomeric structures. For all proteins membrane binding and protection of the membrane structure and integrity has been shown or postulated. Here we discuss the possible membrane chaperoning activity of PspA, IM30 and LiaH and propose that larger oligomeric structures bind to stressed membrane regions, followed by oligomer disassembly and membrane stabilization by protein monomers or smaller/different oligomeric scaffolds.

Organisationseinheit(en)
Institut für Mikrobiologie
Externe Organisation(en)
Johannes Gutenberg-Universität Mainz
Technische Universität Dresden
Typ
Artikel
Journal
Communicative & Integrative Biology
ISSN
1942-0889
Publikationsdatum
19.02.2017
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
Elektronische Version(en)
https://doi.org/10.1080/19420889.2016.1264546 (Zugang: Offen)