Base editors model mitochondrial disease
Abstract
Optimized TALE base editors are used to generate a rat model of mitochondrial disease and then revert the disease mutation in the next generation.
Details
- Organisation(s)
-
Institute of Plant Genetics
- Type
- Article
- Journal
- Nature biotechnology
- ISSN
- 1087-0156
- Publication date
- 03.06.2025
- Publication status
- E-pub ahead of print
- Peer reviewed
- Yes
- Electronic version(s)
-
https://doi.org/10.1038/s41587-025-02706-9 (Access:
Unknown
)
