Dysregulating ClpP

From Antibiotics to Anticancer?

authored by
David A. Dougan, Ingo Hantke, Kürşad Turgay
Abstract

In this issue of Cell Chemical Biology, Wong et al. (2018) identify several dysregulators of a key mitochondrial protease: casein lytic protease P (ClpP). These dysregulators were found to trigger programmed cell death and may offer fresh avenues for the development of novel cancer therapeutics.

Organisation(s)
Institute of Microbiology
External Organisation(s)
La Trobe University
Type
Survey paper
Journal
Cell Chemical Biology
Volume
25
Pages
929-930
No. of pages
2
ISSN
2451-9456
Publication date
16.08.2018
Publication status
Published
Peer reviewed
Yes
ASJC Scopus subject areas
Drug Discovery, Molecular Medicine, Molecular Biology, Biochemistry, Clinical Biochemistry, Pharmacology
Sustainable Development Goals
SDG 3 - Good Health and Well-being
Electronic version(s)
https://doi.org/10.1016/j.chembiol.2018.08.002 (Access: Open)