Das stressige Leben des Bacillus subtilis

authored by
Ingo Hantke, Heinrich Schäfer, Regina Kramer, Kürşad Turgay
Abstract

Here we present Bacillus subtilis as a model system to study protein homeostasis and protein quality control in conjunction with the different layers of its stress response systems. We established a new marker to study protein aggregation in vivo. Furthermore, we observed that the transcription factor Spx, which has already been characterized as a central player to activate transcription of redox-chaperones during heat shock and oxidative stress response, was also able to simultaneously inhibit the transcription of translation-related genes as a second response to stress.

Organisation(s)
Institute of Microbiology
Type
Article
Journal
BioSpektrum
Volume
25
Pages
150-152
No. of pages
3
ISSN
0947-0867
Publication date
01.04.2019
Publication status
Published
ASJC Scopus subject areas
Biotechnology, Molecular Biology
Electronic version(s)
https://doi.org/10.1007/s12268-019-1023-0 (Access: Closed)